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The expiration dating period must be smaller than 38.11 months. Using the initial point x(0) = xref d = 38.11 8, the QNLS algorithm converges to xR = 32.801. Therefore, the expiration dating period for the underlying production batches is 32 months. Minimum Approach for Multiple Batches When the hypothesis for equality of slopes is rejected at the 0.25 signi cance level, the minimum approach should be implemented. This is because the degradation lines of individual batches cannot be considered the same since they have different degradation rates. In this situation the FDA guideline establishes that the overall expiration dating period has to ensure that the product will remain within acceptable limits regardless of the batch from which it comes. Thus, the shelf life for each batch is calculated and the expiration dating period is based on the lowest of all shelf lives. Mathematically, this can be expressed as min {xL(1), . . . , K , xL(k )} (49)

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Character mode is a mode where only O-N-E C-H-A-R-A-C-T-E-R at a time is transmitted. The server will provide an acknowledgment when it receives each character and the echoing is performed by the server. The client, in turn, will send an acknowledgment to the server as well. Line mode is the mode where full-duplex transmission occurs with data being transmitted a line at a time. In line mode, text that is entered by the user is echoed locally and only full lines of data are transmitted to the server. This greatly reduces the number of packets that are required to be transmitted across the network.

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cervical cancers. Obese women appear to be less compliant with general screening recommendations for cervical cancer, and this may explain the increased mortality from all cervical cancers in this group.

Estimation of Required Heat of Pyrolysis for Different Compounds lene (PE) is usually referred as (C2 H4 )n , or

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pattern that would be the most appealing and emphasize the features of the object that were under test The most common type of DIC interferometer is used for qualitative observation of semitransparent biological samples; this system works in transmission and not on re ection Although neither as popular nor as commercially available as white light interference microscopes, a DIC interferometer can also deliver quantitative data about a surface pro le while working in re ective mode Some idea about the optical path difference between sheared wavefronts can be achieved by looking at created interference colors an comparing the to Michel-Levy and Lacroix who came up in 1889 with Interference Color Chart A more reliable technique, one that does not require color comparison and can be used with a black and white CCD camera, is based on phase shifting interferometry (see chapter on Phase Shifting Interferometry and Arnison et al.

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, 2004) The phase shift between interfering beams can be obtained by shifting the Wollaston prism laterally or by rotating the polarizer However, the phase shift will be wavelength dependent, and the fringes will change contrast during the phase shift To avoid this changing contrast, achromatic phase shifting based on the geometric phase can be used (Hariharan, 1996) Once the optical path difference between sheared replica of the wavefront re ected from the object is obtained in two orthogonal directions, the original surface can be calculated The advantage of the DIC interferometer is that it is almost insensitive to vibrations since they are almost common path interferometers The major limitations of these interferometers, which include a short measurable depth and thickness of the object and index gradient, occur because of the limited depth of eld of the objective like in any other nonscanning interference microscope.

H= - = - a 3t'

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