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When run screen-oriented, aumix displays all available audio channels. In screenoriented mode, use keys to highlight and change displayed audio settings. Use PageUp, PageDown, and the up arrow and down arrow keys to select channels. Use the right or left arrow key to increase or decrease volume. Type m to mute the current channel. Press the spacebar to select the current channel as the recording device. If a mouse is available, you can use it to select volume levels, balance levels, or the current recording channel.

There are two main types of genotoxic agents which may induce changes in chromosomal structure and number: physical mutagens (UV light, ionising radiation), and chemical mutagens (organic and inorganic) In most of the cases, mutation of DNA or changes in the genetic information of the cell induced by electrophilic reactants is the primary event in the initiation of carcinogenesis by chemicals; however, it is possible that in some cases, nongenetic changes may be primary events The most important organic carcinogens include the polycyclic aromatic hydrocarbons (PAHs), aromatic amines and aminoazo dyes, dialkyl nitrosamines, alkyl nitrosamines, polychlorinated aliphatic and alicyclic hydrocarbons, a atoxins, pyrrolizidine alkaloids, ethionine, urethane, cycasins and a large array of other alkylating agents Inorganic carcinogens include certain metals (such as chromium, cadmium, lead and mercury) and complex silicates (Casciano, 1991) The induction of chromosome damages is one of the primary events in the initiation of carcinogenesis by chemicals.

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Because there is no truly reliable reference electrode for use in non-aqueous solutions, various reference electrodes have so far been used. Thus, accurate mutual comparison of the potential data in non-aqueous systems is often difficult. In order to improve the situation, the IUPAC Commission on Electrochemistry proposed a method to be used for reporting electrode potentials [8]. It can be summarized as follows: 1. The Fc+/Fc or BCr+/BCr couple is selected as reference redox system and the electrode potentials in any solvent and at any temperature are reported as values referred to the (apparent) standard potential of the system. Which of the two couples to select depends on the potential of the system under study; the potential of the reference redox system should not overlap that of the system under study. Because the difference between the standard potentials of the two couples is almost solvent-independent (1.132 0.012 V, see Table 6.4), the potential referred to one system can be converted to the potential referred to the other.

niques For example, a purchasing director at a small maker of process measurement instruments shared, We re into schedule sharing, and make our production plans and schedules available to our suppliers This has enabled us to reduce our excess and obsolete inventory by some $200,000 last year Other practices that are in current favor include: Moving inventory back to the suppliers This strategy is by far the overwhelming favorite of most purchasing and supply management people when they first assume inventory management responsibility It is often the method of choice to reduce inventory levels and investment, and among the easiest to implement For example, a purchasing manager at a small manufacturer of industrial equipment acknowledges, Our most successful inventory management practice to date has been in shifting both inventory ownership and the physical location back to the suppliers.

Our total purchased items are about $15 million, and we ve been able to negotiate with three of our major suppliers to stock our parts at their facility and deliver them to us on an as-needed basis The savings are not significant, he relates, but the cash flow is helped immensely A purchasing agent at a midsize manufacturer also has benefited from shifting raw inventory to suppliers She tells of reducing inventory by 25%, while achieving a significant increase in inventory turns, from 22 to 30 Embedding a supplier representative on site to manage inventory One of the most creative and innovative programs is that in operation at a midsize manufacturer of medical devices A senior buyer tells of having a distributor s fulltime employee assigned on site who helps to manage our electronics vendors at no cost to me.

Several chemical pollutants can produce carcinogenic effects in sh species through the induction of genetic lesions Indeed, most of these chemicals cause tumours at speci c or multiple sites in sh (Harshbarger & Clark, 1990) Carcinogens are divided into two categories: genotoxic and epigenetic Compounds that react directly or indirectly with DNA are, in most cases, mutagens (polycyclic aromatic hydrocarbons, alkylating agents, speci c metals), and they are designated as genotoxic because they have the potential to alter the genetic material Epigenetic carcinogens, such as organochlorides, estrogens, clo brate, phthalate esters, nitriloacetic acid, etc are those carcinogens that are not classi ed as genotoxic, and a multitude of mechanisms may be involved in the induction of chromosomal damage by these carcinogens (Weisburger & Williams, 1991; Zakrzewski, 1991).

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