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Too often, using email as your task manager turns you reactive. You respond to email messages and issues coming up by email because it makes you feel obligated. But you need a step between getting the email and deciding what to do. You need to make sure that you keep your own priorities in mind when you go from email message to task. So don t use your inbox as your task list. Besides, an email message subject doesn t necessarily tell you exactly what your task is. Or the message might contain multiple tasks. Restating and unpacking tasks from email will help you manage your work better. Use an email client such as Outlook that supports task management or install a task manager into your email application. For example, todocue (todocue.com) can add a to-do list to Gmail via a Firefox extension. Or use a to-do manager that works via email such as Backpack, Remember the Milk or Toodledo. Toodledo and Remember the Milk let you forward email to a special address where the messages are added as to dos.

In Eqs. (3.3.5) and (3.3.6), is the total length of the transmission line, Vi s is the voltage vector of the incident wave at x 0, and Vr s is that of the re ected wave at x . At the end points, x 0 and x , Eqs. (3.3.5) and (3.3.6) yield

$288,057 274,172 166,768 147,819 131,369 123,228 110,327 108,003 101,302 95,893

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Alternatively, due to the degenerative nature of the genetic code ( sense mutations), or through changes in non-coding regions ( silent mutations), mutations may have no phenotypic effect It is generally recognised that the majority of adaptive evolutionary change results from point mutations, representing relatively small genomic changes, which may lead to the production of novel proteins Such events may be detected using molecular genetic techniques and are likely, in part, to underpin adaptive responses to environmental stress (Hoffmann & Parsons, 1991; Hillis et al, 1996) Such mutations may generate variants that lead to observable intraspeci c genetic variability in susceptibility to pollutants in natural populations (Depledge, 1994) An understanding of the dynamics and signi cance of point mutations is therefore central to assessing the impacts of genotoxins and associated genotypic response.

2002 SURVEY OF CREDIT PORTFOLIO MANAGEMENT PRACTICES Do you explicitly evaluate the performance of your portfolio(s) of credit assets Yes No If yes, Return on Assets or Return on Equity Return on Regulatory Capital RAROC (Risk Adjusted Return on Economic Capital) NIACC (Net Income After Capital Charge) Sharpe Ratio (or Information Ratio) Other 17% 17% 78% 31% 14% 8% These responses sum to greater than 100%, because many respondents checked more than one answer. 90% 10%

Frameshift mutations: A frameshift mutation alters the reading frame of the genetic code through the addition or deletion of one or more bases Such changes may modify an entire sequence and hence alter the transcription of a gene, frequently leading to the production of non-functional gene products Chromosomal mutations: Chromosomal mutations (aberrations) involve changes to the gross structure of chromosomes, resulting from the loss, breakage and reunion of genetic material during cell replication Such events can give rise to deletions, inversions and translocations, and occasionally gene ampli cation The latter has been shown to underlay genetic adaptation to chemical stress (Field et al, 1989) Strand breakages occur under normal conditions but exposure to genotoxins can increase the amount (Shugart & Theodorakis, 1994).

For example, ionising radiation can cause strand breakage directly, whereas other physical agents such as UV light or genotoxic chemicals can modify DNA molecules that are involved in DNA repair (eg photoproducts, adducts, modi ed bases), and thus promote strand breaks Genomic mutations: Genomic mutations produce changes in the number of chromosomes (aneuploidy), and usually result from exposure to a substance that interferes with the mitotic apparatus during cell division The majority of aneuploidies are lethal, but a small proportion do survive with reduced viability and may play an important role in the generation of genetic diseases such as neoplasia (Dixon & Clarke, 1982)..

0.55 0.642 0.35 10) 0.319 0.13 1) 0.164 0.12 1) 0.08 3) 0.21 1, 10) 0.50 1) 0.56 0.277 0.71 1) 0.07 10) 0.040 1) 0.05 1) 0.434 0.69 1)

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