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as activity, or ignoring pain) to be associated with adaptive functioning, and passive coping strategies (depending on others for help in pain control and restricted activities) to be related to greater pain and depression (Boothby, Thorn, Stroud, & Jensen, 1999) However, beyond this, there is no evidence supporting the greater effectiveness of any one active coping strategy compared to any other (Turk, Meichenbaum, & Genest, 1983) It seems more likely that different strategies will be more effective than others for some people at some times but not necessarily for all people all of the time A number of studies have been demonstrated that if patients are instructed in the use of adaptive coping strategies, their rating of intensity of pain decreases and tolerance of pain increases (Boothby et al, 1999).

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Future research is needed to determine the biological markers associated with the potential intensity thresholds and the implications for both in-task and postexercise affective responses and the impact on exercise adoption and adherence Brain-Derived Neurotrophic Factor Hypothesis In the section on cognitive function, BDNF was shown to be involved in mediating the beneficial effects of exercise on brain plasticity Brain-derived neurotrophic factor is one of several neurotrophic factors that support the health of glutamatergic neurons, which connect to cognitive, sensory, and motor regions of the brain (Cotman & EngesserCesar, 2002), and BDNF also has antidepressant effects (Siuciak, Lewis, Wiegand, & Lindsay, 1997) Hippocampal levels of BDNF have been shown to increase with either exercise or antidepressant drugs (Russo-Neustadt, Ha, Ramirez, & Kesslak, 2001; Van Hoomissen, Chambliss, Holmes, & Dishman, 2003) Additionally, Van Hoomisen et al.

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The most important factor in poor coping appears to be the presence of catastrophic thinking, not the nature of speci c adaptive coping strategies (Sullivan et al, 2001) Given our discussion of the psychological factors that play a role in pain, we can now consider how these factors can be integrated within a multidimensional model of pain Pain is a complex subjective phenomenon comprising a range of factors, each of which contributes to the interpretation of nociception as pain Thus, each person uniquely experiences pain A signi cant factor contributing to the current situation relates to diagnostic uncertainty The diagnosis of pain is not an exact science A major problem in understanding pain is that it is a subjective (internal) state There is no pain thermometer that can accurately measure the amount of pain a person feels or should be experiencing.

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found that exercise also enhanced BDNF mRNA in the ventral tegmental area /substantia nigra, which is associated with mesolimbic dopaminergic function RussoNeustadt et al found that exercise combined with an antidepressant drug hastened the time it took BDNF levels to increase in the rat brain If either exercise or antidepressant medication is used alone, it can take up to 2 weeks for BDNF levels to increase, similar to the time that it takes drugs to begin to be effective in treating anxiety and depressive disorders In combination, Russo-Neustadt et al noted, drugs and exercise can increase BDNF levels in as little as 2 days, though this additive effect has not been consistently found (Van Hoomisen et al, 2003) Overall, though, this has led Cotman and Engesser-Cesar (2002, p.

Duplicate copies of the list of rooms occupied and any special notes on whether the occupants are children or physically challenged will aid in the rescue efforts Front of ce personnel must remain calm throughout the ordeal The switchboard will be active, with calls from inside and outside the hotel Requests for information from the re emergency crew and rst-aid and rescue squad will be mixed with phone calls from the media and persons related to hotel guests Switchboard operators should keep phone calls brief so the phone lines are open Security should not be forgotten during crises Some people will take advantage of the confusion to loot and pilfer Cash drawers and other documents should be secured Each hotel must develop its own communications procedure for a re Each plan will vary, based on the strengths of the employees in the front of ce.

An integrative model of chronic pain and acute recurrent pain needs to incorporate the mutual interrelationships among physical, psychosocial, and behavioral factors and the changes that occur among these relationships over time A model that focuses on only one of these sets of factors will inevitably be incomplete The physiological model proposed by Melzack and Wall (1965) can be contrasted with the more psychological, cognitive-behavioral (biobehavioral) model that Turk and colleagues (Turk, 1996; Turk & Flor, 1999) have proposed Melzack and Wall focus primarily on the basic anatomy and physiology of pain; whereas, Turk and colleagues have emphasized the in uence of psychological processes on physical factors underlying the experience of pain Yet both incorporate physical and psychological factors to account for the experience of pain.

78) to suggest that exercise may decrease the time required for antidepressants to be effective, a finding that is potentially clinically significant..

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