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What is defeat Nothing but education, nothing but the first step to getting better It is defeat that turns the bones to flint and gristle to muscle and makes men invincible and forms those basic natures that are now in ascendancy in the world Do not be afraid of defeat

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Mental toughness is the willingness, day in and day out, to keep the commitments you make to yourself It is singleness of purpose, also one of Lombardi s favorite phrases It is the ability to stay motivated, no matter what obstacles rear up in front of you

reabsorption, so the amount of medullary water absorption is greatly exceeded by the amount not reabsorbed, ie, excreted Figure 6 7 summarizes the previously described changes in volume and osmolality of the tubular fluid as it flows along the nephron and emphasizes how, once fluid enters the collecting-duct system, the osmolality depends very much on the levels of ADH

LOMBARDI RULE #9

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The reabsorption of most of the filtered water, anions, and osmotic content is linked to the active reabsorption of sodium In all conditions, the vast majority of the filtered volume is reabsorbed iso-osmotically in the proximal tubule in a manner that is entirely dependent on active sodium reabsorption The capacity to generate a variable-osmolality urine depends on separating salt from water in the diluting segments Reabsorption of water remaining in the lumen beyond the loop of Henle is variable, depending on hydration status, allowing the kidneys to excrete either a highvolume dilute urine, a low-volume concentrated urine, or anything in between Levels of ADH determine whether the hypo-osmotic fluid leaving the diluting segments is excreted largely as is or whether most of this fluid is subsequently reabsorbed The existence of the medullary osmotic gradient depends on (1) transport of salt without water into the medullary interstitium by the thick ascending limb, (2) recycling of urea, and (3) low-volume countercurrent blood flow in the vasa recta

pendent programming language); JINI, (Sun s ad-hoc networking software, which uses a message-passing middleware layer between the software components of the core system); and Javaspace The latter technology provides a distributed messaging capability and functions with JINI to enable different software components to communicate seamlessly within the home network despite being hosted on different hardware platforms (eg, Windows NT4, Red Hat Linux, et cetera) All of the communications systems work in tandem with environmentally friendly recycling and energy/water conserving systems

Be mentally tough Use your toughness to beat setbacks Use your toughness to seek out new challenges

6 1 A man ingests 12 g of sodium/day His nonrenal loss (gastrointestinal tract and sweat) is 04 g/day In the steady state, what amount of sodium chloride is excreted daily in the urine Mannitol is a substance sometimes infused to reduce cerebral edema It is handled by the kidneys similarly to inulin What effect would a large mannitol infusion have on sodium excretion A No effect B Increase sodium excretion C Reduce sodium excretion

Mental toughness is also the determination to look forward and seek out the next challenge, pushing the organization in new directions and acting, rather than simply reacting We don t persevere just to keep breathing; we persevere to prevail and, ultimately, to win And this is character in action

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W H AT I T TA K E S T O B E # 1

BasiC renal proCesses for sodium, Chloride, and Water / 101

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Own your habits Search out and identify your beliefs and the habits that grow out of them Use your courage When necessary, pick flight but otherwise, be brave Fight! Embrace your passion Jump into your passion with both feet and bring others along with you Be prepared to sacrifice Sacrifice and self-denial lie behind every success Demand total commitment Demand it first from yourself and then from others around you Weed out the uncommitted The organization that wins is populated by winners Work at it Don t buy the myth of the overnight success Invest in your talent Be disciplined on and off the field Discipline takes different forms, but it always pertains Be mentally tough Use your toughness to beat setbacks Use your toughness to seek out new challenges

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INSPIRING OTHERS TO GREATNESS:

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