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TSH hypersecretion by the pituitary may be caused by a tumor and is a rare cause of hyperthyroidism Serum TSH is elevated or normal (determined by a sensitive TSH assay) in the presence of true thyrotoxicosis Hyperthyroidism may also be due to pituitary hyperplasia, in which case it is known as nonneoplastic inappropriate secretion of thyrotropin Pituitary hyperplasia may be detected on MRI scan as pituitary enlargement without a discrete adenoma being visible This condition appears to be due to a diminished feedback effect of T4 upon the pituitary It may be familial, but it can also be caused by prolonged untreated hypothyroidism, especially in youth

Calculate three separate cases: whether the two parents can ride together, just Bob and Charlie, and just the kids. Exercise 4-4. Now it s time for a little high school math. Take a sphere of radius 5. Calculate and output the surface area, and the volume of the sphere. Then use the ternary operator to indicate which of the two is greater. Make Pi a constant float, and use a value of 3.14159 for precision. You should probably also make the radius a constant.

Hashimoto s thyroiditis may cause transient hyperthyroidism during the initial destructive phase This is also seen in some patients receiving interferon- , interferon- , and interleukin-2

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The prevalence of hyperthyroidism in pregnancy most commonly due to Graves disease is about 02% Struma ovarii is rare Newborns have an increased risk of intrauterine growth retardation, prematurity, and transient thyrotoxicosis from transplacental transfer of TSH-R Ab[stim] Postpartum thyroiditis is common, occurring in 5 9% of women in the first 6 months after delivery Transient hyperthyroidism results from the release of stored thyroid hormone following damage to the thyroid (see Thyroiditis, below) Although hCG generally has a low affinity for the thyroid s TSH receptors, very high serum levels of hCG may cause sufficient receptor activation to cause thyrotoxicosis Mild gestational hyperthyroidism may occur during the first 4 months of pregnancy, when hCG levels are very high Pregnant women are more likely to have thyrotoxicosis and hyperemesis gravidarum if they have high serum

many users. This transformation would not have been possible without advances in computer hardware (such as the advent of transistors and improvements in memory technology), the falling cost of hardware, and increased government funding of research projects. Digital computer networks were a natural outgrowth of time-sharing, and these technologies formed the theoretical and operational foundation that led directly to the present day Internet. CTSS One of the first time-sharing systems, developed at MIT by Professor Fernando Corbat , was Compatible Timesharing System (CTSS).6 CTSS was important for several reasons, but mainly it laid the groundwork for future time-sharing systems such as MULTICS, DTSS, and UNIX. MULTICS Around this time, the Department of Defense s Advanced Research Projects Agency (ARPA) began to aggressively fund many research projects designed to further the nation s computing defense infrastructure. Dr. J. C. R. Linklider, head of ARPA s Information Processing Techniques Office (IPTO), was responsible for choosing and funding many of the most important projects that undertook the development of time-sharing systems. Linklider was a true visionary and is one of the most important and influential thinkers in the history of computing. One of the projects funded under Linklider was Project MAC, and one of the most significant descendants of Project MAC was MULTiplexed Information and Computing Service (MULTICS).7 MULTICS was a joint project between MIT, General Electric, and Bell Labs. Bell Labs had been looking for a replacement for its BESYS operating system and decided that MULTICS was the answer (Pierce 1985, 59). The project goals were laid out in six papers presented at the 1965 Fall Joint Computer Conference (http://www.multicians.org/papers.html). The Bell Lab contingent included Ken Thompson, Dennis Ritchie, M. D. McIlroy, and Joe Ossanna.

Autonomous toxic adenomas of the thyroid may be single (Plummer s disease) or multiple (toxic multinodular goiter) These adenomas are not accompanied by infiltrative ophthalmopathy or dermopathy Antithyroid antibodies are usually not present in the plasma, and tests for TSH-R Ab[stim] are negative

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Subacute thyroiditis typically presents with a moderately enlarged, tender thyroid, and hyperthyroidism It is thought to be due to a viral infection If the gland is nontender, the disorder is called silent thyroiditis Hyperthyroidism is followed by hypothyroidism During thyrotoxicosis, thyroid radioactive iodine (RAI) uptake is low A similar problem is

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