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(2008) The befores and afters of molecular replacement Acta Crystallographica D Biological Crystallography, 64, 17 24 A review of molecular replacement Glusker, JP, Lewis, M and Rossi, M (1994) Crystal Structure Analysis for Chemists and Biologists, VCH, New York A superbly readable, comprehensive and accessible description of X-ray crystallography Karplus, PA and Faerman, C (1994) Ordered water in macromolecular structure Current Opinion in Structural Biology, 4, 770 6 A mini-review of structural water at protein surfaces Ke, HM (1997) Overview of isomorphous replacement phasing Methods in Enzymology, 276, 448 61 A review of isomorphous replacement McPherson, A (1990) Current approaches to macromolecular crystallisation European Journal of Biochemistry, 189, 1 23 A review of the process of protein crystallisation McPherson, A (2004) Introduction to protein crystallization Methods, 34, 254 65 An excellent introduction to crystallization of proteins McPherson, A and Cudney, B.

Now Playing Window: The bottom left of the screen contains a video window that displays either a live TV channel or a recorded TV program. Clicking on the Now Playing window switches the viewing of the program to full screen. Recently Recorded: Lists any shows that have been recorded. Clicking on one takes you to a menu where you can learn more about the show, play it, delete it, and decide how long to keep the recording. Scheduled Recordings: Lists any scheduled recordings. Clicking on one enables you to nd out about the show, cancel the recording, or prioritize it. The My TV list: In the upper left of the My TV screen is the list that includes the following items: Live TV: Click this button to switch to full-screen viewing of TV. Recorded TV: This button takes you to a full listing of recorded TV shows and enables you to sort them, schedule new recordings, and view shows that are scheduled to be recorded. Guide: The Guide button enables you to switch to the Program Guide. Search: To nd a TV program, the Search button takes you to an on-screen search menu that can be easily worked from a keyboard or from a remote control. You can use a variety of search criteria to nd the shows you want.

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(2006) Searching for the silver bullets: An alternative strategy for crystallizing macromolecules Journal of Structural Biology, 156, 387 406 A fascinating development in increasing the success of crystallization screens Messerschmidt, A (2007) X-ray Crystallography of Biomacromolecules Wiley-VCH Verlag GmbH, Weinheim A comprehensive description of current practice in X-ray diffraction Qian, B , Raman, S, Das, R et al (2007) High-resolution structure prediction and the crystallographic phase problem Nature, 450, 259 64 A new modelling method which offers improved solution to the phase problem including de novo structure prediction Schwartz, T, Rould, MA, Lowenhaupt, K et al (1999) Crystal structure of the Z domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA Science, 284, 1841 5 A good example of structure determination of a DNA protein macromolecular complex Stewart, I (1997) Crystallography of a golf ball Scienti c American, 276, 96 8.

An entertaining description of the mathematics of symmetry taking golf balls as a concrete example!.

Before you continue, you need to choose Debug Break on Error. When you select this menu option, Visual LISP enables you to jump to the error in your source code automatically. Using the function Error-Prone-Code produces an error because strcat concatenates strings, as the following demonstrates. You can type this at the console:

Uncertainty (module 1)

The control charts discussed earlier are very useful in the diagnostic aspects of quality process improvement They can be used to stabilize a process by identifying out-of-control situations After the process is stabilized and brought in control, further improvement of the process can be achieved by using some special control charts such as the cumulative sum (CUSUM) control chart and the exponentially weighted moving average (EWMA) control chart These control charts can be used when small shifts in a process are of interest CUSUM Control Chart A CUSUM chart provides an ef cient way of detecting small shifts in the mean of a process (<1/2 ) For larger shifts (>1/2 ), the x chart is usually used The CUSUM chart incorporates information contained in a sequence of sample points It keeps track of the cumulative sum of the deviations between each sample point (a sample mean) and a target value.

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